The gospel of corneal blindness! No donor cornea required!

2022-08-12

On October 8, 2019, on the eve of the annual "world eye care day", the World Health Organization released the world's first "world vision report", which aroused the world's high attention to problems such as visual disability and blindness.


The report points out that more than 2.2 billion people worldwide have visual impairment or blindness. Among all kinds of blinding eye diseases, keratopathy is second only to cataract. At present, there are about 60 million patients with corneal blindness in the world.


The human eye is an extremely complex and precise organ. If the human eye is compared to a camera, then the cornea is equivalent to a camera lens, and corneal transplantation is like changing a lens for a camera.


The first 1 / 6 transparent part of the outermost layer of the eyeball wall is known as the cornea. It is mainly composed of avascular connective tissue, with a complexity of about 1mm. It looks like a concave convex lens and has the function of refracting light. It plays an extremely important role in visual imaging.


Corneal transplantation is often the most effective rehabilitation method for patients with visual impairment caused by corneal opacity caused by various reasons. Most patients with corneal blindness can "regain light" by conventional donor corneal transplantation.


However, due to the number of donor corneas, the lack of information in cornea database, and the limited corneas are not fully utilized, cornea donors are still in a state of serious shortage. Many patients with corneal diseases are in the "dark" for life due to the deterioration of their condition while waiting for corneal donors.


In the face of the serious shortage of donor corneas that can "bring dawn" to corneal blind patients, the research and development of artificial corneas has always been the pursuit of scientists. In addition, corneal blind patients who have suffered severe corneal thermal burn and chemical injury and have generated neovascularization are prone to rejection reaction after receiving donor corneal transplantation, which leads to failure of vision restoration surgery.


For these patients, implantation of artificial cornea is the only choice for their rehabilitation.


The essence of Michaelis artificial cornea is a special refractive device based on artificial synthetic materials, which can be used to replace the turbid cornea that affects the optical path of the eyeball after the lesion, so that the patient can see the light again.


Globally, a "Boston type" artificial cornea developed by Harvard Medical School has been used for dry clinical treatment. However, the "Boston type" artificial cornea needs to be installed in the middle of the donor cornea, and the donor cornea is used as the carrier. This not only does not save the use of the donor cornea, but also aggravates the waste of the donor cornea, which is not in line with China's national conditions.


Fortunately, the continuous development of science and technology has made new breakthroughs in the research and development of artificial corneas made of pure artificial materials.


Michaelis artificial cornea is made of artificial materials, which is helpful to alleviate the shortage of corneal donors in China. As a new technology successfully developed, Michal artificial cornea is not only safe in operation, good in treatment effect, but also low in treatment cost.


At the same time, it has been superior to all similar products at home and abroad in terms of indications. All patients with bilateral corneal blindness, including corneal transplantation failure, severe keratoconjunctival scar vascularization caused by chemical injury, thermal burn and explosion injury, eyelid atresia, severe autoimmune diseases (such as Stevens Johnson syndrome and cicatricial pemphigoid), and corneal blindness caused by end-stage dry eye, who are difficult to succeed in corneal transplantation, can be restored to vision with Mich artificial cornea.


In the past, corneal thermal burn and chemical injury were "incurable diseases" for patients. The success rate of using donor cornea for transplantation was almost zero, and there was almost no possibility of seeing light again. However, with the advent of MIH artificial cornea technology, these patients have rekindled the hope of vision restoration.


In the past, many patients with severe corneal chemical injury caused by gas explosion and chemical explosion achieved vision restoration by implanting Michal artificial cornea with the efforts of medical expert team.


Compared with the donor cornea, the artificial cornea will not be attacked by the human immune system and will not produce autoimmune rejection. Once implanted, the artificial cornea can be used for life.